Findings from a 2011 study on testosterone supplementation for men showed that it generally takes from 3 weeks to 6 months before noticeable results. Depending on what you want testosterone boosters to do will affect the amount of time it takes to notice any change. 

Sexual Desire

Testosterone’s impact on sexual desire develops after three weeks and plateaus at six weeks. Afterward, it can remain stable for up to 6 months. After taking testosterone boosters, you are likely to notice an improvement in your sex life [1].

Ejaculation and Erection

Most men find improvement in erections and ejaculation after only three weeks. However, it can take as long as six months for erections to reach their full potential with testosterone boosters. After six months, changes in ejaculation and erection may still occur. 

Body Composition

Changes to body composition, including lean and fat mass and muscle strength, can appear within 12 to 20 weeks. They should stabilize at around 6 to 12 months. While this number varies from person to person, after taking testosterone boosters for several months, it can significantly affect the way the body looks.

Lean body mass tends to increase within 3 or 4 months. This is around the same time that you might notice less body fat. This type of change occurs because testosterone gets the body to prioritize building lean muscle mass over storing fat. With a regular workout regime, testosterone can cause an increase in muscle size and overall mass [2].

Depression

Testosterone’s impact on a depressed mood is noticeable after around 3 to 6 weeks of taking these boosters. You can expect your general quality of life to improve at around this time as the depression potentially fades. These effects have a maximum impact after 18 to 30 weeks. 

Bone Strength 

One of the slower benefits of testosterone boosters is their effect on the bones. Studies have found that bone strength improves after six months of taking prescription testosterone boosters [3]. Bone health tends to improve for at least three more years until it has reached maximum strength.

Natural testosterone boosters can be safe, effective alternatives to prescription testosterone treatment.

Insulin Sensitivity

For men with diabetes, testosterone boosters might offer dramatic improvements. Insulin sensitivity might improve within only a few days. However, the full effects on a person’s glycemic control only manifest after three months to a year. It is recommended to continue taking diabetes medicines even if you feel well and regularly visit your doctor to adjust the dosage [4].

Inflammation

Low levels of testosterone have been linked with an increase in metabolic risk and systemic inflammation. Improvements in inflammation tend to occur at around 3 to 12 weeks. If you have an autoimmune condition such as Crohn’s disease, you may continue to see improvements for up to 24 months [5].  

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References

1. Kent, A. “Testosterone and Sexual Desire” US. National Library of Medicine. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673004/ 
2. Saad, Aversa, et al. “Onset of effects of testosterone treatment and time span until maximum effects are achieved” US. National Library of Medicine. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188848/ 
3. Lazarev, Artemii, and Eduard Bezuglov. “Testosterone Boosters Intake in Athletes: Current Evidence and Further Directions.” MDPI, Multidisciplinary Digital Publishing Institute, 17 May 2021. 
4. B;, Skrajnowska D;Bobrowska-Korczak. “Role of Zinc in Immune System and Anti-Cancer Defense Mechanisms.” Nutrients, U.S. National Library of Medicine, .  
5. F, Jockenhövel. “Testosterone Therapy–What, When and to Whom?” The Aging Male” : The Official Journal of the International Society for the Study of the Aging Male, U.S. National Library of Medicine. 
6. Kire Stojkoviski, et al. “Testosterone Boosters in 2022: Best Supplements to Increase Testosterone Levels” The Sacramento Bee, May 5, 2022. 
7. Tirabassi, Biagioli, et al. “Bone benefits of testosterone replacement therapy in male hypogonadism.” US. National Library of Medicine. https://pubmed.ncbi.nlm.nih.gov/24994579/ 
8. Pitteloud N;Mootha VK;Dwyer AA;Hardin M;Lee H;Eriksson KF;Tripathy D;Yialamas M;Groop L;Elahi D;Hayes FJ; “Relationship between Testosterone Levels, Insulin Sensitivity, and Mitochondrial Function in Men.” Diabetes Care, U.S. National Library of Medicine, https://pubmed.ncbi.nlm.nih.gov/15983313/. 
9. Bianchi, Vittorio Emanuele. “The Anti-Inflammatory Effects of Testosterone.” Journal of the Endocrine Society, Endocrine Society, 22 Oct. 2018, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299269/.